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Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

Myofibroblast differentiation plays a critical role in wound healing and in the pathogenesis of fibrosis. We have previously shown that myofibroblast differentiation is mediated by the activity of serum response factor (SRF), which is tightly controlled by the actin polymerization state. In this stu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sandbo, Nathan, Ngam, Caitlyn, Torr, Elizabeth, Kregel, Steve, Kach, Jacob, Dulin, Nickolai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668708/
https://ncbi.nlm.nih.gov/pubmed/23580645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464461
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