Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

Myofibroblast differentiation plays a critical role in wound healing and in the pathogenesis of fibrosis. We have previously shown that myofibroblast differentiation is mediated by the activity of serum response factor (SRF), which is tightly controlled by the actin polymerization state. In this stu...

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Autores principales: Sandbo, Nathan, Ngam, Caitlyn, Torr, Elizabeth, Kregel, Steve, Kach, Jacob, Dulin, Nickolai
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668708/
https://ncbi.nlm.nih.gov/pubmed/23580645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464461
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