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Regulation of Yorkie activity in Drosophila imaginal discs by the Hedgehog receptor gene patched

The Hedgehog (Hh) pathway was first defined by its role in segment polarity in the Drosophila melanogaster embryonic epidermis and has since been linked to many aspects of vertebrate development and disease. In humans, mutation of the Patched1 (PTCH1) gene, which encodes an inhibitor of Hh signaling...

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Detalhes bibliográficos
Main Authors: Kagey, Jacob D., Brown, Jordan A., Moberg, Kenneth H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668547/
https://ncbi.nlm.nih.gov/pubmed/22705500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2012.05.007
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