Small molecule antagonism of oxysterol-induced Epstein–Barr virus induced gene 2 (EBI2) activation()

The Epstein–Barr virus induced gene 2 (EBI2) was recently identified as the first oxysterol-activated 7TM receptor. EBI2 is essential for B cell trafficking within lymphoid tissues and thus the humoral immune response in general. Here we characterize the antagonism of the non-peptide molecule GSK682...

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Hlavní autoři: Benned-Jensen, Tau, Madsen, Christian M., Arfelt, Kristine N., Smethurst, Christian, Blanchard, Andy, Jepras, Robert, Rosenkilde, Mette M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668520/
https://ncbi.nlm.nih.gov/pubmed/23772388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.02.003
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