New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) – The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations()

The systematic use of antivitamin K anticoagulants (AVK) as rodenticides caused the selection of rats resistant to AVKs. The resistance is mainly associated to genetic polymorphisms in the Vkorc1 gene encoding the VKORC1 enzyme responsible for the reduction of vitamin K 2,3-epoxide to vitamin K. Fiv...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Matagrin, Benjamin, Hodroge, Ahmed, Montagut-Romans, Adrien, Andru, Julie, Fourel, Isabelle, Besse, Stéphane, Benoit, Etienne, Lattard, Virginie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668507/
https://ncbi.nlm.nih.gov/pubmed/23772386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.02.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados