A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation

BACKGROUND: Ex vivo colospheres have been previously characterised as a colorectal cancer (CRC) well-rounded multicellular model, exclusively formed by carcinoma cells, and derived from fresh CRC tissue after mechanical dissociation. The ability to form colospheres was correlated with tumour aggress...

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Detalhes bibliográficos
Main Authors: Weiswald, L-B, Richon, S, Massonnet, G, Guinebretière, J-M, Vacher, S, Laurendeau, I, Cottu, P, Marangoni, E, Nemati, F, Validire, P, Bellet, D, Bièche, I, Dangles-Marie, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668460/
https://ncbi.nlm.nih.gov/pubmed/23538387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.132
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