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FOXO3 Gene Variants and Human Aging: Coding Variants May Not Be Key Players

FOXO3 is generally recognized as a “master” gene in aging since its association with longevity has been replicated in multiple organisms and human populations. A group of single nucleotide polymorphisms in linkage disequilibrium with a coding region has been associated with human longevity, but the...

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Detalhes bibliográficos
Main Authors: Donlon, Timothy A., Curb, J. David, He, Qimei, Grove, John S., Masaki, Kamal H., Rodriguez, Beatriz, Elliott, Ayako, Willcox, D. Craig, Willcox, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668389/
https://ncbi.nlm.nih.gov/pubmed/22459618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gls067
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