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Upregulation of myeloid cell leukemia-1 potentially modulates beclin-1-dependent autophagy in ischemic stroke in rats

BACKGROUND: The mechanisms that underlie autophagy in cerebral ischemia remain poorly defined. Myeloid cell leukemia-1 (Mcl1), an anti-apoptotic member of the Bcl-2 family of proteins, regulates the balance between autophagy and apoptosis. However, little is known regarding its expression profile an...

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Hlavní autoři: Xingyong, Chen, Xicui, Sun, Huanxing, Su, Jingsong, Ou, Yi, Huang, Xu, Zhang, Ruxun, Huang, Zhong, Pei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668241/
https://ncbi.nlm.nih.gov/pubmed/23688351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-56
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