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Differential ability of a T-antigen transport-defective mutant of simian virus 40 to transform primary and established rodent cells.

The transforming potential and oncogenicity of a simian virus 40 (SV40) mutant affecting T-antigen (T-ag), SV40(cT)-3, was examined in an effort to dissect T-ag functions in transformation. SV40(cT)-3 has a point mutation at nucleotide 4434 that abolishes the transport of T-ag to the nucleus but doe...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Lanford, R E, Wong, C, Butel, J S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.5.1043
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