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Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma

Human papillomavirus (HPV) types associated with head and neck cancer generally induce a robust immune response. Despite the establishment of such an inflammatory microenvironment, HPV is able to persist and promote malignant transformation. The PD-1:PD-L1 immune checkpoint may play a critical role...

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Detalhes bibliográficos
Autor principal: Pai, Sara I.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667901/
https://ncbi.nlm.nih.gov/pubmed/23762795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24065
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