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Shab K(+) channel slow inactivation: A test for U-type inactivation and a hypothesis regarding K(+)-facilitated inactivation mechanisms
Herein, we report the first characterization of Shab slow inactivation. Open Shab channels inactivate within seconds, with two voltage-independent time constants. Additionally, Shab presents significant closed-state inactivation. We found that with short depolarizing pulses, shorter than the slowest...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667890/ https://ncbi.nlm.nih.gov/pubmed/23419584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.23569 |
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