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Differential inhibition of the TRPM8 ion channel by Gα(q) and Gα(11)
Cold temperature is encoded by the cold-sensitive ion channel TRPM8 in somatosensory neurons. It has been unclear how TRPM8 is modulated so that it can mediate distinct type of cold signaling. We have recently reported that activated Gα(q) directly inhibits TRPM8 after activation of Gq-coupled recep...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667880/ https://ncbi.nlm.nih.gov/pubmed/23334401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.23466 |
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