Mechanistic Model of Rothia mucilaginosa Adaptation toward Persistence in the CF Lung, Based on a Genome Reconstructed from Metagenomic Data

The impaired mucociliary clearance in individuals with Cystic Fibrosis (CF) enables opportunistic pathogens to colonize CF lungs. Here we show that Rothia mucilaginosa is a common CF opportunist that was present in 83% of our patient cohort, almost as prevalent as Pseudomonas aeruginosa (89%). Seque...

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Detalhes bibliográficos
Main Authors: Lim, Yan Wei, Schmieder, Robert, Haynes, Matthew, Furlan, Mike, Matthews, T. David, Whiteson, Katrine, Poole, Stephen J., Hayes, Christopher S., Low, David A., Maughan, Heather, Edwards, Robert, Conrad, Douglas, Rohwer, Forest
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667864/
https://ncbi.nlm.nih.gov/pubmed/23737977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064285
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