HIV-1 Tat Protein Increases Microglial Outward K(+) Current and Resultant Neurotoxic Activity

Microglia plays a crucial role in the pathogenesis of HIV-1-associated neurocognitive disorders. Increasing evidence indicates the voltage-gated potassium (K(v)) channels are involved in the regulation of microglia function, prompting us to hypothesize K(v) channels may also be involved in microglia...

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Main Authors: Liu, Jianuo, Xu, Peng, Collins, Cory, Liu, Han, Zhang, Jingdong, Keblesh, James P., Xiong, Huangui
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667810/
https://ncbi.nlm.nih.gov/pubmed/23738010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064904
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