HIV-1gp120 Induces Neuronal Apoptosis through Enhancement of 4-Aminopyridine-Senstive Outward K(+) Currents

Human immunodeficiency virus type 1 (HIV-1)-associated dementia (HAD) usually occurs late in the course of HIV-1 infection and the mechanisms underlying HAD pathogenesis are not well understood. Accumulating evidence indicates that neuronal voltage-gated potassium (Kv) channels play an important rol...

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Main Authors: Chen, Lina, Liu, Jianuo, Xu, Changshui, Keblesh, James, Zang, Weijin, Xiong, Huangui
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189248/
https://ncbi.nlm.nih.gov/pubmed/22016798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025994
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