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Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia

Focal degradation of extracellular matrix (ECM) is the first step in the invasion of cancer cells. MT1-MMP is a potent membrane proteinase employed by aggressive cancer cells. In our previous study, we reported that MT1-MMP was preferentially located at membrane protrusions called invadopodia, where...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Watanabe, Ayako, Hosino, Daisuke, Koshikawa, Naohiko, Seiki, Motoharu, Suzuki, Takashi, Ichikawa, Kazuhisa
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667784/
https://ncbi.nlm.nih.gov/pubmed/23737743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003086
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