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Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

Important knowledge about the determinants of complex human phenotypes can be obtained from the estimation of heritability, the fraction of phenotypic variation in a population that is determined by genetic factors. Here, we make use of extensive phenotype data in Iceland, long-range phased genotype...

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Autores principales: Zaitlen, Noah, Kraft, Peter, Patterson, Nick, Pasaniuc, Bogdan, Bhatia, Gaurav, Pollack, Samuela, Price, Alkes L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667752/
https://ncbi.nlm.nih.gov/pubmed/23737753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003520
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