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Both PDI and PDIp Can Attack the Native Disulfide Bonds in Thermally-Unfolded RNase and Form Stable Disulfide-Linked Complexes

Protein disulfide isomerase (PDI) and its pancreatic homolog (PDIp) are folding catalysts for the formation, reduction, and/or isomerization of disulfide bonds in substrate proteins. However, the question as to whether PDI and PDIp can directly attack the native disulfide bonds in substrate proteins...

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Detalhes bibliográficos
Main Authors: Fu, Xin-Miao, Zhu, Bao Ting
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667393/
https://ncbi.nlm.nih.gov/pubmed/21238616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2011.01.004
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