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Conformational basis for substrate recruitment in Protein Tyrosine Phosphatase 10D()

The coordinated activity of Protein Tyrosine Phosphatases (PTP) is crucial to initiate, modulate and terminate diverse cellular processes. The catalytic activity of this protein depends on a nucleophilic cysteine at the active site that mediates the hydrolysis of the incoming phosphotyrosine substra...

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Hlavní autoři: Madan, Lalima L., Gopal, B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667199/
https://ncbi.nlm.nih.gov/pubmed/22007620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201092q
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