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Conformational basis for substrate recruitment in Protein Tyrosine Phosphatase 10D()

The coordinated activity of Protein Tyrosine Phosphatases (PTP) is crucial to initiate, modulate and terminate diverse cellular processes. The catalytic activity of this protein depends on a nucleophilic cysteine at the active site that mediates the hydrolysis of the incoming phosphotyrosine substra...

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Detalhes bibliográficos
Main Authors: Madan, Lalima L., Gopal, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667199/
https://ncbi.nlm.nih.gov/pubmed/22007620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201092q
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