Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss

AIMS/HYPOTHESIS: Insulin resistance (IR) improves with weight loss, but this response is heterogeneous. We hypothesised that metabolomic profiling would identify biomarkers predicting changes in IR with weight loss. METHODS: Targeted mass spectrometry-based profiling of 60 metabolites, plus biochemi...

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Detalhes bibliográficos
Main Authors: Shah, S. H., Crosslin, D. R., Haynes, C. S., Nelson, S., Turer, C. B., Stevens, R. D., Muehlbauer, M. J., Wenner, B. R., Bain, J. R., Laferrère, B., Gorroochurn, P., Teixeira, J., Brantley, P. J., Stevens, V. J., Hollis, J. F., Appel, L. J., Lien, L. F., Batch, B., Newgard, C. B., Svetkey, L. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667157/
https://ncbi.nlm.nih.gov/pubmed/22065088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2356-5
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