To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture

Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). Given that fully reprogrammed cells are highly proliferative and escape from cellul...

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Detalhes bibliográficos
Main Authors: Willmann, Charlotte A., Hemeda, Hatim, Pieper, Lisa A., Lenz, Michael, Qin, Jie, Joussen, Sylvia, Sontag, Stephanie, Wanek, Paul, Denecke, Bernd, Schüler, Herdit M., Zenke, Martin, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667031/
https://ncbi.nlm.nih.gov/pubmed/23734247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065324
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