Rapid 16S rRNA Next-Generation Sequencing of Polymicrobial Clinical Samples for Diagnosis of Complex Bacterial Infections

Classifying individual bacterial species comprising complex, polymicrobial patient specimens remains a challenge for culture-based and molecular microbiology techniques in common clinical use. We therefore adapted practices from metagenomics research to rapidly catalog the bacterial composition of c...

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Bibliographic Details
Main Authors: Salipante, Stephen J., Sengupta, Dhruba J., Rosenthal, Christopher, Costa, Gina, Spangler, Jessica, Sims, Elizabeth H., Jacobs, Michael A., Miller, Samuel I., Hoogestraat, Daniel R., Cookson, Brad T., McCoy, Connor, Matsen, Frederick A., Shendure, Jay, Lee, Clarence C., Harkins, Timothy T., Hoffman, Noah G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666980/
https://ncbi.nlm.nih.gov/pubmed/23734239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065226
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