Rapid 16S rRNA Next-Generation Sequencing of Polymicrobial Clinical Samples for Diagnosis of Complex Bacterial Infections

Classifying individual bacterial species comprising complex, polymicrobial patient specimens remains a challenge for culture-based and molecular microbiology techniques in common clinical use. We therefore adapted practices from metagenomics research to rapidly catalog the bacterial composition of c...

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Detalhes bibliográficos
Main Authors: Salipante, Stephen J., Sengupta, Dhruba J., Rosenthal, Christopher, Costa, Gina, Spangler, Jessica, Sims, Elizabeth H., Jacobs, Michael A., Miller, Samuel I., Hoogestraat, Daniel R., Cookson, Brad T., McCoy, Connor, Matsen, Frederick A., Shendure, Jay, Lee, Clarence C., Harkins, Timothy T., Hoffman, Noah G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666980/
https://ncbi.nlm.nih.gov/pubmed/23734239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065226
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