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Activated hepatic stellate cells: Negative regulators of hepatocyte proliferation in liver diseases

Tissue homeostasis requires an effective, limited wound-healing response to injury. In chronic disease, failure to regenerate parenchymal tissue leads to the replacement of lost cellular mass with a fibrotic matrix. The mechanisms that dictate the balance of cell regeneration and fibrogenesis are no...

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Autori principali: Chung, Chuhan, Iwakiri, Yasuko
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666938/
https://ncbi.nlm.nih.gov/pubmed/22876366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25761
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