Sequence Conservation of the Region Targeted by the Abbott RealTime HBV Viral Load Assay in Clinical Specimens

The Abbott RealTime HBV assay targets the N-terminal region of the S gene. Here we analyzed the sequence variability of the assay target region from >2,100 clinical specimens. Thermodynamic modeling of the percentage of bound primer/probe at the assay annealing temperature was performed to assess...

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Main Authors: Cloherty, Gavin A., Rhoads, James, Young, Thomas P., Parkin, Neil T., Holzmayer, Vera, Yuen, Lilly, Mullen, Carolyn
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Virology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666792/
https://ncbi.nlm.nih.gov/pubmed/23345287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03003-12
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