Sequence Conservation of the Region Targeted by the Abbott RealTime HCV Viral Load Assay

The Abbott RealTime (RT) HCV assay targets the 5′ untranslated region (UTR) of the HCV genome. Here, we analyzed the sequence variability of the assay target regions from 1,092 specimens. Thermodynamic modeling of the percentage of primers/probes bound at the assay annealing temperature was performe...

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Main Authors: Cloherty, Gavin, Parkin, Neil, Rhoads, James, Esping, Claudia, Steinhart, Corklin, Schneider, George, Yuen, Lily, Hackett, John
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Virology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993474/
https://ncbi.nlm.nih.gov/pubmed/24430453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02661-13
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