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Sequence Conservation of the Region Targeted by the Abbott RealTime HCV Viral Load Assay

The Abbott RealTime (RT) HCV assay targets the 5′ untranslated region (UTR) of the HCV genome. Here, we analyzed the sequence variability of the assay target regions from 1,092 specimens. Thermodynamic modeling of the percentage of primers/probes bound at the assay annealing temperature was performe...

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Autores principales: Cloherty, Gavin, Parkin, Neil, Rhoads, James, Esping, Claudia, Steinhart, Corklin, Schneider, George, Yuen, Lily, Hackett, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993474/
https://ncbi.nlm.nih.gov/pubmed/24430453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02661-13
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