Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis

Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood. Here we identify the glucocorticoid receptor (GR) target gene, serum- and glucocorticoid-inducible kinase 1 (SGK1), as one such mechanism. Using a human h...

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Main Authors: Anacker, Christoph, Cattaneo, Annamaria, Musaelyan, Ksenia, Zunszain, Patricia A., Horowitz, Mark, Molteni, Raffaella, Luoni, Alessia, Calabrese, Francesca, Tansey, Katherine, Gennarelli, Massimo, Thuret, Sandrine, Price, Jack, Uher, Rudolf, Riva, Marco A., Pariante, Carmine M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666742/
https://ncbi.nlm.nih.gov/pubmed/23650397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300886110
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