Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis

Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood. Here we identify the glucocorticoid receptor (GR) target gene, serum- and glucocorticoid-inducible kinase 1 (SGK1), as one such mechanism. Using a human h...

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Detalhes bibliográficos
Main Authors: Anacker, Christoph, Cattaneo, Annamaria, Musaelyan, Ksenia, Zunszain, Patricia A., Horowitz, Mark, Molteni, Raffaella, Luoni, Alessia, Calabrese, Francesca, Tansey, Katherine, Gennarelli, Massimo, Thuret, Sandrine, Price, Jack, Uher, Rudolf, Riva, Marco A., Pariante, Carmine M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666742/
https://ncbi.nlm.nih.gov/pubmed/23650397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300886110
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