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Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites

Complement C1q is a hexameric molecule assembled from 18 polypeptide chains of three different types encoded by three genes. This versatile recognition protein senses a wide variety of immune and nonimmune ligands, including pathogens and altered self components, and triggers the classical complemen...

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Detalhes bibliográficos
Main Authors: Bally, Isabelle, Ancelet, Sarah, Moriscot, Christine, Gonnet, Florence, Mantovani, Alberto, Daniel, Régis, Schoehn, Guy, Arlaud, Gérard J., Thielens, Nicole M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666734/
https://ncbi.nlm.nih.gov/pubmed/23650384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304894110
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