CaBP1, a neuronal Ca(2)(+) sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions

Calcium-binding protein 1 (CaBP1) is a neuron-specific member of the calmodulin superfamily that regulates several Ca(2+) channels, including inositol 1,4,5-trisphosphate receptors (InsP(3)Rs). CaBP1 alone does not affect InsP(3)R activity, but it inhibits InsP(3)-evoked Ca(2+) release by slowing th...

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Hlavní autoři: Li, Congmin, Enomoto, Masahiro, Rossi, Ana M., Seo, Min-Duk, Rahman, Taufiq, Stathopulos, Peter B., Taylor, Colin W., Ikura, Mitsuhiko, Ames, James B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666712/
https://ncbi.nlm.nih.gov/pubmed/23650371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220847110
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