VEGF Blockade Enables Oncolytic Cancer Virotherapy in Part by Modulating Intratumoral Myeloid Cells

Understanding the host response to oncolytic viruses is important to maximize their antitumor efficacy. Despite robust cytotoxicity and high virus production of an oncolytic herpes simplex virus (oHSV) in cultured human sarcoma cells, intratumoral (ITu) virus injection resulted in only mild antitumo...

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Detalhes bibliográficos
Main Authors: Currier, Mark A, Eshun, Francis K, Sholl, Allyson, Chernoguz, Artur, Crawford, Kelly, Divanovic, Senad, Boon, Louis, Goins, William F, Frischer, Jason S, Collins, Margaret H, Leddon, Jennifer L, Baird, William H, Haseley, Amy, Streby, Keri A, Wang, Pin-Yi, Hendrickson, Brett W, Brekken, Rolf A, Kaur, Balveen, Hildeman, David, Cripe, Timothy P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666636/
https://ncbi.nlm.nih.gov/pubmed/23481323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.39
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