The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice

The purpose of this study was to explore how genetic deletion and pharmacological antagonism of the P2X7 receptor (P2rx7) alter mood-related behaviour, gene expression and stress reactivity in the brain. The forced swim test (FST), tail suspension test (TST) and amphetamine-induced hyperlocomotion (...

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Detalhes bibliográficos
Main Authors: Csölle, Cecilia, Andó, Rómeó D., Kittel, Ágnes, Gölöncsér, Flóra, Baranyi, Mária, Soproni, Krisztina, Zelena, Dóra, Haller, József, Németh, Tamás, Mócsai, Attila, Sperlágh, Beáta
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666310/
https://ncbi.nlm.nih.gov/pubmed/22243662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145711001933
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