Cargando...
Deregulated G1–S control and energy stress contribute to the synthetic-lethal interactions between inactivation of RB and TSC1 or TSC2
Synthetic lethality is a potential strategy for cancer treatment by specifically promoting the death of cancer cells with particular defects such as the loss of the RB (RB1) tumor suppressor. We previously showed that inactivation of both RB and TSC2 induces synergistic apoptosis during the developm...
Gardado en:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists
2013
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666254/ https://ncbi.nlm.nih.gov/pubmed/23447678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.121301 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|