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The cell polarity scaffold Lethal Giant Larvae regulates synapse morphology and function

Lethal Giant Larvae (LGL) is a cytosolic cell polarity scaffold whose loss dominantly enhances neuromuscular junction (NMJ) synaptic overgrowth caused by loss of the Fragile X Mental Retardation Protein (FMRP). However, direct roles for LGL in NMJ morphological and functional development have not be...

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Autors principals: Staples, Jon, Broadie, Kendal
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666253/
https://ncbi.nlm.nih.gov/pubmed/23444371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.120139
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