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Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis

The tumor suppressor lethal giant larvae (Lgl) plays a critical role in epithelial cell polarization. However, the molecular mechanism by which Lgl carries out its functions is unclear. In this study, we report that the yeast Lgl proteins Sro7p and Sro77p directly interact with Exo84p, which is a co...

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Autores principales: Zhang, Xiaoyu, Wang, Puyue, Gangar, Akanksha, Zhang, Jian, Brennwald, Patrick, TerBush, Daniel, Guo, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171422/
https://ncbi.nlm.nih.gov/pubmed/16027223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502055
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