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Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis

The tumor suppressor lethal giant larvae (Lgl) plays a critical role in epithelial cell polarization. However, the molecular mechanism by which Lgl carries out its functions is unclear. In this study, we report that the yeast Lgl proteins Sro7p and Sro77p directly interact with Exo84p, which is a co...

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Bibliographic Details
Main Authors: Zhang, Xiaoyu, Wang, Puyue, Gangar, Akanksha, Zhang, Jian, Brennwald, Patrick, TerBush, Daniel, Guo, Wei
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171422/
https://ncbi.nlm.nih.gov/pubmed/16027223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502055
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