Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

Decoquinate (DQ) is highly effective at killing malaria parasites in vitro; however, it is extremely insoluble in water. In this study, solid dispersion method was used for DQ formulation which created a suitable physical form of DQ in aqueous phase for particle manipulation. Among many polymers and...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wang, Hongxing, Li, Qigui, Reyes, Sean, Zhang, Jing, Xie, Lisa, Melendez, Victor, Hickman, Mark, Kozar, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666196/
https://ncbi.nlm.nih.gov/pubmed/23766925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/769234
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars