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An Automated System for Monitoring and Regulating the pH of Bicarbonate Buffers
The bicarbonate buffer is considered as the most biorelevant buffer system for the simulation of intestinal conditions. However, its use in dissolution testing of solid oral dosage forms is very limited. The reason for this is the thermodynamic instability of the solution containing hydrogen carbona...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer US
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666009/ https://ncbi.nlm.nih.gov/pubmed/23468339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9933-5 |
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