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Development and Evaluation of Sustained-Release Etoposide-Loaded Poly(ε-Caprolactone) Implants
Poly(ε-caprolactone) implants containing etoposide, an important chemotherapeutic agent and topoisomerase II inhibitor, were fabricated by a melt method and characterized in terms of content uniformity, morphology, drug physical state, and sterility. In vitro and in vivo drug release from the implan...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer US
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666007/ https://ncbi.nlm.nih.gov/pubmed/23666789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9977-6 |
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