Conversion of Human Umbilical Cord Mesenchymal Stem Cells in Wharton’s Jelly to Dopamine Neurons Mediated by the Lmx1a and Neurturin In Vitro: Potential Therapeutic Application for Parkinson’s Disease in a Rhesus Monkey Model

hUC-MSCs hold great promise in vitro neuronal differentiation and therapy for neurodegenerative disorders including Parkinson’s disease. Recent studies provided that Lmx1α play an important role in the midbrain dopamine cells differentiation. Neurturin is desired candidate gene for providing a neuro...

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Detalhes bibliográficos
Main Authors: Yan, Min, Sun, Maosheng, Zhou, Yan, Wang, Wanpu, He, Zhanlong, Tang, Donghong, Lu, Shuaiyao, Wang, Xiaonan, Li, Song, Wang, Wenju, Li, Hongjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665802/
https://ncbi.nlm.nih.gov/pubmed/23724014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064000
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