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Comparison of Treatment Effect Estimates for Pharmacological Randomized Controlled Trials Enrolling Older Adults Only and Those including Adults: A Meta-Epidemiological Study

CONTEXT: Older adults are underrepresented in clinical research. To assess therapeutic efficacy in older patients, some randomized controlled trials (RCTs) include older adults only. OBJECTIVE: To compare treatment effects between RCTs including older adults only (elderly RCTs) and RCTs including al...

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Autors principals: Seegers, Valérie, Trinquart, Ludovic, Boutron, Isabelle, Ravaud, Philippe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665786/
https://ncbi.nlm.nih.gov/pubmed/23723992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063677
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