Impact of single centre status on estimates of intervention effects in trials with continuous outcomes: meta-epidemiological study

Objective To compare estimates of intervention effects between single centre and multicentre randomised controlled trials with continuous outcomes. Design Meta-epidemiological study. Data sources 26 meta-analyses totalling 292 randomised controlled trials (177 single centre, 115 multicentre) with co...

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Bibliografiske detaljer
Main Authors: Bafeta, Aïda, Dechartres, Agnes, Trinquart, Ludovic, Yavchitz, Amélie, Boutron, Isabelle, Ravaud, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group Ltd. 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279328/
https://ncbi.nlm.nih.gov/pubmed/22334559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.e813
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