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Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

Exosomes are 30–150 nm vesicles secreted by a wide range of mammalian cells that can contain microRNA (miRNA). To test if marrow stromal cell (MSC) exosomes could be used as a vehicle for delivery of anti-tumor miRNAs, we transfected MSCs with a miR-146b expression plasmid, and harvested exosomes re...

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Detalhes bibliográficos
Main Authors: Katakowski, Mark, Buller, Ben, Zheng, Xuguang, Lu, Yong, Rogers, Thomas, Osobamiro, Oyinkansola, Shu, Wayne, Jiang, Feng, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665755/
https://ncbi.nlm.nih.gov/pubmed/23419525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.019
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