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Preclinical Evaluation of NETA-Based Bifunctional Ligand for Radioimmunotherapy Applications using (212)Bi and (213)Bi: Radiolabeling, Serum Stability, and Biodistribution and Tumor Uptake Studies
INTRODUCTION: Despite the great potential of targeted α-radioimmunotherapy (RIT) as demonstrated by pre-clinical and clinical trials, limited progress has been made on the improvement of chelation chemistry for (212)Bi and (213)Bi. A new bifunctional ligand 3p-C-NETA was evaluated for targeted α RIT...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665654/ https://ncbi.nlm.nih.gov/pubmed/23541026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.01.012 |
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