Motoneuron Differentiation of Induced Pluripotent Stem Cells from SOD1G93A Mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder mainly affecting motor neurons. Mutations in superoxide dismutase-1 (SOD-1) account for about 20% of familial ALS patients. A robust supply of motoneurons carrying the mutated gene would help understand the causes of motoneuron deat...

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Detalhes bibliográficos
Main Authors: Yao, Xiao-Li, Ye, Cheng-Hui, Liu, Qiang, Wan, Jian-bo, Zhen, Jun, Xiang, Andy Peng, Li, Wei-Qiang, Wang, Yitao, Su, Huangxing, Lu, Xi-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665598/
https://ncbi.nlm.nih.gov/pubmed/23724084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064720
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