Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF

Background: Amyotrophic lateral sclerosis (ALS) is an incurable fatal motoneuron disease with a lifetime risk of approximately 1:400. It is characterized by progressive weakness, muscle wasting, and death ensuing 3–5 years after diagnosis. Granulocyte-colony stimulating factor (G-CSF) is a drug cand...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Henriques, Alexandre, Kastner, Stefan, Chatzikonstantinou, Eva, Pitzer, Claudia, Plaas, Christian, Kirsch, Friederike, Wafzig, Oliver, Krüger, Carola, Spoelgen, Robert, Gonzalez De Aguilar, Jose-Luis, Gretz, Norbert, Schneider, Armin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299451/
https://ncbi.nlm.nih.gov/pubmed/25653590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00464
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