Beta(2)-Adrenoceptor Stimulation Suppresses TLR9-Dependent IFNA1 Secretion in Human Peripheral Blood Mononuclear Cells

INTRODUCTION: IFNA1 (interferon alpha) is a key cytokine regulating the activity of numerous immune cells. Plasmacytoid dendritic cells (pDCs) as natural interferon-producing cells play critical roles as sensors of pathogens and link innate to adaptive immunity. CpG motifs within DNA sequences activ...

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Detalhes bibliográficos
Main Authors: Hilbert, Tobias, Bongartz, Josef, Weisheit, Christina, Knüfermann, Pascal, Baumgarten, Georg, Hoeft, Andreas, Poth, Jens M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665595/
https://ncbi.nlm.nih.gov/pubmed/23724117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065024
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