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Histone Deacetylases and NF-kB Signaling Coordinate Expression of CX3CL1 in Epithelial Cells in Response to Microbial Challenge by Suppressing miR-424 and miR-503

The NF-kB pathway is key to epithelial immune defense and has been implicated in secretion of antimicrobial peptides, release of cytokines/chemokines to mobilize immune effector cells, and activation of adaptive immunity. The expression of many inflammatory genes following infection involves the rem...

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Detalhes bibliográficos
Main Authors: Zhou, Rui, Gong, Ai-Yu, Chen, Dongqing, Miller, Ryan E., Eischeid, Alex N., Chen, Xian-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665534/
https://ncbi.nlm.nih.gov/pubmed/23724129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065153
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