Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens

Nicotine and methamphetamine (METH) cause addiction by triggering neuroplastic changes in brain reward pathways though they each engage distinct molecular targets (nicotine receptors and dopamine transporters respectively). Addiction to both drugs is very prevalent, with the vast majority of METH us...

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Main Authors: Saint-Preux, Fabienne, Bores, Lorena Rodríguez, Tulloch, Ingrid, Ladenheim, Bruce, Kim, Ronald, Thanos, Panayotis K., Volkow, Nora D., Cadet, Jean Lud
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665347/
https://ncbi.nlm.nih.gov/pubmed/23562942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.03.052
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