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Ikaros, CK2 kinase, and the road to leukemia
Ikaros encodes a zinc finger protein that is essential for hematopoiesis and that acts as a tumor suppressor in leukemia. Ikaros function depends on its ability to localize to pericentromeric heterochromatin (PC-HC). Ikaros protein binds to the upstream regulatory elements of target genes, aids in t...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665334/ https://ncbi.nlm.nih.gov/pubmed/21750978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-011-0964-5 |
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